منابع مشابه
3-(Trimethylsilyl)prop-2-ynyl p-toluenesulfonate
In the title compound, C(13)H(18)O(3)SSi, the SO(3) group displays a partial rotational (ca 50°) disorder about the C-S bond, with relative proportions 0.7744 (13):0.2256 (13). This disorder also forces the propynyl CH(2) group to be disordered.
متن کامل5-(Prop-2-ynyl)-5H-dibenzo[b,f]azepine
The asymmetric unit of the title compound, C(17)H(13)N, contains two independent butterfly-shaped mol-ecules. The seven-membered azepine rings both adopt a boat conformation. The dihedral angles between the benzene rings in the two mol-ecules are 46.95 (11) and 52.21 (11)°.
متن کامل1-Prop-2-ynyl-1H-benzimidazol-2-amine
In the title compound, C(10)H(9)N(3), the benzimidazol-2-amine and CH(2)-C CH units are not coplanar, with a dihedral angle of 60.36° between their mean planes. The crystal structure is stabilized by inter-molecular N-H⋯N hydrogen bonding and π-π inter-actions [centroid-centroid distances 3.677 (1) and 3.580 (1) Å], assembling the mol-ecules into a supra-molecular structure with a three-dimensi...
متن کاملMonoamine oxidase inhibitors: benzylidene-prop-2-ynyl-amines analogues.
A new series of benzylidene-prop-2-ynyl-amines analogues have been synthesized and evaluated for their monoamine oxidase A and B inhibitory activity by determination of IC(50) and selectivity index (SI). Among these inhibitors, benzhydrylidene-prop-2-ynyl-amine (2, IC(50)=32 nM) and (3, 4-dimethoxy-benzylidene)-prop-2-ynyl-amine (10, IC(50)=14 nM) provide the highest inhibitory potency toward m...
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The flavin-dependent thymidylate synthase X (ThyX), rare in eukaryotes and completely absent in humans, is crucial in the metabolism of thymidine (a DNA precursor) in many microorganisms including several human pathogens. Conserved in mycobacteria, including Mycobacterium leprae, and Mycobacterium tuberculosis, it represents a prospective anti-mycobacterial therapeutic target. In a M. tuberculo...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2012
ISSN: 1600-5368
DOI: 10.1107/s1600536812007866